Zocor® (Simvastatin) and Kidney Damage

One of the possible side effects of Zocor® (simvastatin) can lead to kidney damage in some patients. Rhabdomyolysis, a known side effect of the statin medication, is a rare form of a muscle condition called myopathy. Myopathy is a more common side effect of this medication and is characterized by unexplained muscle weakness or pain.

Rhabdomyolysis occurs when fibers from damaged muscle tissue are released into the blood stream. The broken down muscle tissue is eliminated from the body through the kidneys. In severe cases, the kidneys may become overworked while trying to rid the body of the excess tissue (myoglobin). This can result in death from acute kidney failure.

Patients are also at risk of kidney failure because as the myoglobin breaks down, it can block the structures of the kidneys.

Kidney Damage Symptoms

Symptoms of kidney damage include:

  • Abnormal-colored urine (dark, red or cola colored)
  • Overall weakness
  • Muscle stiffness or aching
  • Muscle tenderness
  • Weakness of the affected muscles
  • Joint Pain
  • Seizures
  • Unintentional weight gain

Aside from kidney failure, there are other kidney-related complications that can arise as a result of rhabdomyolysis. These complications include acute tubular necrosis (ATN) and acute renal failure. ATN is a kidney disorder in which the tubular cells of the kidneys are damaged, resulting in kidney failure. It is caused by a lack of oxygen to the kidney tissue. Acute renal failure is the sudden inability for the kidneys to remove waste and concentrate urine without losing electrolytes.

The outlook for people who suffer kidney failure as a result of Zocor® use depends on the extent of kidney damage. Patients who receive treatment soon after rhabdomyolysis has been detected have a reduced risk of chronic kidney damage. People with milder cases may return to normal activity within a few weeks or a month. Patients with more severe causes may continue to have problems with fatigue and muscle pain.

Contact Our Zocor® Lawyers Today

If you were prescribed Zocor® and were diagnosed with kidney failure, you may be eligible to file a claim to seek compensation for your loss. To learn more, please contact a Zocor® lawyer today.

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